4.2.3: Official Definition
4.X.X
[RFC3463] (Standards Track) from the The Internet Engineering Task Force (IETF) definition for codes that start with 4.X.X:
A persistent transient failure is one in which the message as sent is valid, but persistence of some temporary condition has caused abandonment or delay of attempts to send the message. If this code accompanies a delivery failure report, sending in the future may be successful.
X.2.3
[RFC3463] (Standards Track) from the The Internet Engineering Task Force (IETF) definition for codes that end with X.2.3:
A per-mailbox administrative message length limit has been exceeded. This status code should be used when the per-mailbox message length limit is less than the general system limit. This code should be used as a permanent failure.